一、个人简介
帅琪，女，汉族，生于1980年8月，陕西西安人，中共党员，四级教授，博士生导师。所指导的研究生获“国家奖学金”，“校长奖学金”，“优秀研究生”，“优秀研究生干部”和“优秀毕业生”等称号。
二、学习与工作经历
1.学习经历
1.2005-09 至 2008-06，西北大学，无机化学，博士
2.2003-09 至 2005-07，西北大学，无机化学，硕士
3.1999-09 至 2003-07，西北大学，应用化学，学士
2.工作经历
1.2019-01 至 今，西北农林科技大学，化学与药学院，教授
2.2017-01 至 2018-12，西北农林科技大学，化学与药学院，副教授
3.2012-01 至 2016-12，西北农林科技大学，理学院，副教授
4.2008-06 至 2011-12，西北农林科技大学，理学院，讲师
三、研究课题
1.基于光热干预和微量热优化的脲酶黑色素纳米马达的构建及抗癌研究，主持，国家自然科学基金面上项目，22073075
2.二茂铁配合物@石墨烯核壳结构与癌细胞作用过程的QCM热动力学研究，主持，国家自然科学基金面上项目，21473136
3.碱土金属二茂铁羧酸功能配合物抑制小麦病原菌生长代谢作用的生物微量热研究，主持，国家自然科学基金青年基金，21103140
4.基于透明质酸靶向及聚集诱导发光成像介导的纳米载药体系应用于光动/乏氧激活联合治疗的抗癌研究，主持，陕西省科技计划项目2022SF-006
四、研究领域
1.纳米马达的设计合成、仿生修饰及生物医学应用
2.伤口敷料的研发及性能研究（抑菌/止血/自愈合/伤口修复）
3.药物修饰、载药、药物传送以及药物与癌细胞靶向作用过程中的热动力学研究
4.功能配合物的设计、合成、结构研究与应用（抑菌/抗癌等）
五、开设课程
为本科讲授《无机化学》、《无机及分析化学》、《无机及分析化学实验》、食工国际全英文课程《General Chemistry》等。参与编著教材（《无机及分析化学》第四版，呼世斌、王进义、吴秋华主编，高等教育出版社）。
六、主要科研成果与学术论文
期刊论文：
1.Xiaoyu Zhao, Chenglong Xue, Yu Liu , Tao Wang and Qi Shuai*, Glu and GSH double-unlocked immunomodulatory tri-cascade nanoreactor for biofilm-infected diabetic wounds healing, Chemical Engineering Journal, 485 (2024) 150002.
2. Li Zhang , Yu Liu , Shupeng Liu , Tao Wang , Feng Ouyang , Zhichao Pei , Yixia Ren and Qi Shuai*, NIR-intervened thermally accelerated urease-propelled MOF nanosubmarine for antibiotic-free antibacterial inhibition via single-wavelength synergistic PDT/PTT, International Journal of Biological Macromolecules, 282 (2024) 137367.
3. Fubin Huang, Chenglong Xue, Xiaoyu Zhao, Yu Liu and Qi Shuai*, Thermal accelerated urease-driven hyaluronan-targeted melanin nano-missile for bio-radar detection and chemodrug-free phototherapy. International Journal of Biological Macromolecules, 267 (2024) 131286.
4. Yu Liu, Li Zhang, Feng Ouyang, Chenglong Xue, Xiaoyu Zhao, Tao Wang, Zhichao Pei, and Qi Shuai*, Thermal-Accelerated Urease-Driven Bowl-Like Polydopamine Nanorobot for Targeted Photothermal/Photodynamic Antibiotic-Free Antibacterial Therapy, Advanced Healthcare Materals, 2024, 2304086.
5.Tao Wang, Chenglong Xue, Xiaoyu Zhao , Yu Liu , Yuqian Wang , Lijin Shi, and Qi Shuai* ,Single NIR laser-activated synergistic low-temperature photothermal therapy and self-oxygenated photodynamic therapy nano-platforms for bacteria infection, Dyes and Pigments, 225 (2024) 112066.
6. Feng Ouyang, Yu Liu, Li Zhang, and Qi Shuai*, Hyaluronic acid-targeted dual-bubble/photothermal-driven nanomissile for enhanced “four-in-one” anti-tumor strategy, International Journal of Biological Macromolecules, 277 (2024) 133997.
7. Xiaoyu Zhao, Chenglong Xue, Tao Wang, Yu Liu, and Qi Shuai*. A novel photothermal combined silver-based melanin nanoparticle for efficient antibacterial and enhanced catalysis of organic pollutants. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 676 (2023) 132273 .
8. Feng Ouyang, Li Zhang, Yu Liu, and Qi Shuai*. Environmentally responsive multistage gas/enzyme/NIR-driven chemotactic transport nanorockets for single wavelength procedural combination therapy. Materials Today Chemistry. 30 (2023) 101533.
9. Zhicheng Liu, Shupeng Liu, Xiaoyu Zhao, Chenglong Xue, Yu Liu, and Qi Shuai*. Photothermal-accelerated urease-powered human serum albumin nanomotor for rapid and efficient photothermal and photodynamic cancer combination therapy. International Journal of Biological Macromolecules. 240 (2023) 124486.
10. Feng Ouyang, Li Zhao, and Qi Shuai*. NIR-activated acid-response “four-in-one” nanomotor for photothermal therapy, chemodynamic therapy and hypoxic-activated chemotherapy. Inorganic Chemistry Communications. 156 (2023) 111325.
11. Feng Ouyang, Li Zhao, and Qi Shuai*. Photothermally driven degradable nanomissile for single-wavelength phototherapy and hypoxia-activated chemotherapy. Inorganic Chemistry Communications. 157 (2023) 111310.
12. Feng Ouyang, Xiaoli Zhang, Li Zhang, Yu Liu, and Qi Shuai*. Enhanced photo-hypoxia-activated combination therapy traced by AIE photosensitizer and targeted by hyaluronic acid: Disulphide bond interference of detoxification barrier. Journal of Photochemistry & Photobiology, B: Biology. 234 (2022) 112535.
13. Chenglong Xue, Xiaomei Xu, Li Zhang, Yu Liu, Shupeng Liu, Zhicheng Liu, Mingyuan Wu, and Qi Shuai*. Self-healing/pH-responsive/inherently antibacterial polysaccharide-based hydrogel for a photothermal strengthened wound dressing. Colloids and Surfaces B: Biointerfaces. 218 (2022) 112738 .
14. Mingyuan Wu, Shupeng Liu, Zhicheng Liu, Fubin Huang, Xiaomei Xu, and Qi Shuai*. Photothermal interference urease-powered polydopamine nanomotor for enhanced propulsion and synergistic therapy. Colloids and Surfaces B: Biointerfaces. 212 (2022) 112353 .
15. Shupeng Liu, Zhicheng Liu, Mingyuan Wu, Xiaomei Xu, Fubin Huang, Li Zhang, Yu Liu, and Qi Shuai*. NIR as a “trigger switch” for rapid phase change, on-demand release, and photothermal synergistic antibacterial treatment with chitosan-based temperature-sensitive hydrogel. International Journal of Biological Macromolecules, 191 (2021) , 344.
16. Jie Yu, Xiaoli Zhang, Zhichao Pei, and Qi Shuai*. A triple-stimulus responsive melanin-based nanoplatform with an aggregation-induced emission-active photosensitiser for imaging-guided targeted synergistic hototherapy/hypoxia-activated chemotherapy. Journal of Materials Chemistry B, 9 (2021) , 9142.
17. Xia Hong, Xiaomei Xu, Zhicheng Liu, Shupeng Liu, Jie Yu, Mingyuan Wu, Yuwei Ma, and Qi Shuai*. Hyaluronan-fullerene/AIEgen nanogel as CD44-targeted delivery of tirapazamine for synergistic photodynamic-hypoxia activated therapy. Nanotechnology, 32 (2021) , 465701 (11pp).
18. Xiuling Xu, Bingbing Zheng, Hongxia Deng, Xiaoli Zhang, and Qi Shuai*. Synthesis and sensing behavior of a new multichannel sensor based onthiazolyl ferrocene-rhodamine for Hg2+ detection. Microchemical Journal, 2020, 158, 105257.
19. Xiuling Xu, Xiaoli Zhang, Cuilan Cao, Bingbing Zheng, Hongxia Deng, and Qi Shuai*. Cu2+-selective naked-eye 'off-on' fluorescent probe with multisignals: chromaticity, fluorescence, electrochemistry. Luminescence. 35 (2020) , 1142.
20. Xiuling Xu, Fan Hu, and Qi Shuai*. Click Chemistry-Assisted Synthesis of a β‑D‑Galactose-Targeted SiO2@RC Shell−Core Structure as a Nanoplatform for Metal-Based Complex Delivery. Inorganic Chemistry, 57 (2018) , 10694.
21. Saisai Yan, Fan Hu, Xia Hong, and Qi Shuai*. Water-soluble ferrocene complexes (WFCs) functionalized silica nanospheres for WFC delivery in HepG2 tumor therapy. Materials Science & Engineering C, 90(2018) , 397.
22. Yuwei Ma, Huiyi Zhou, Fan Hu, Zhichao Pei, Yongqian Xu, and Qi Shuai*. Multifunctional nanogel engineering with redoxresponsive and AIEgen features for the targeted delivery of doxorubicin hydrochloride with enhanced antitumor efficiency and real-time intracellular imaging. Artificial Cells, Nanomedicine, and Biotechnology, 46(2018) , S900.
23. Xiuling Xu, Fan Hu, Yuwei Ma, Jinming Gao and Qi Shuai*. Facile microwave synthesis, structural diversity and herbicidal activity of six novel alkaline-earth metal complexes (AECs) based on skeletal isomerization chlorophenoxyacetic acids. New Journal of Chemistry, 42,(2018) , 4155.
专利：
1. 一种透明质酸-黑色素纳米粒子的制备方法（授权号：CN110787294B）。
2. 一种脲酶驱动人血清蛋白纳米粒子及其制备方法（授权号：CN110812340B）。
七、联系方式
通讯地址：西北农林科技大学（北校区）化学与药学院（E426）
邮编：712100
