一、 个人简介
母海钵,副教授,硕士生导师。2016年博士毕业于西北农林科技大学化学与药学院,同年留校从事教学科研工作。
学术兼职:中国生物化学与分子生物学会复合糖专业委员会青年委员。
二、 科研项目
1. 国家自然科学基金青年项目(NSFC31700707)
2. 陕西省自然科学基础研究计划一般项目(2018JQ2007)
三、 研究领域
1. 基于糖类的药物设计及应用
2. 抗生素药物递送系统的设计及应用
四、承担课程
《蛋白质与酶化学》、《工程化学》、《无机及分析化学实验》
五 、近5年主要学术论文
1. Mu H, Bai H, Sun F, Liu Y, Lu C, Qiu Y, Chen P, Yang Y, Kong L, Duan J*. Pathogen-targeting glycovesicles as a therapy for salmonellosis. Nature Communications 2019, 10(1):4039.
2. Wang Z, Bai H, Lu C, Hou C, Qiu Y, Zhang P, Duan J, Mu H*. Light controllable chitosan micelles with ROS generation and essential oil release for the treatment of bacterial biofilm. Carbohydrate Polymers 2019, 205:533-539.
3. Hou Y, Wang Z, Zhang P, Bai H, Sun Y, Duan J, Mu H*. Lysozyme Associated Liposomal Gentamicin Inhibits Bacterial Biofilm. International Journal of Molecular Science 2017, 18(4).
4. Mu H, Tang J, Liu Q, Sun C, Wang T, Duan J*. Potent Antibacterial Nanoparticles against Biofilm and Intracellular Bacteria. Scientific Reports 2016, 6:18877.
5. Mu H, Niu H, Wang D, Sun F, Sun Y, Duan J*. Chitosan conjugation enables intracellular bacteria susceptible to aminoglycoside antibiotic. Glycobiology 2016, 26(11):1190-1197.
6. Mu H, Liu Q, Niu H, Wang D, Tang J, Duan J*. Autophagy promotes DNA-protein crosslink clearance. Mutation Research Genetic Toxicology and Environmental Mutagenesis 2016, 797:21-25.
7. Li Z, Liu Y, Zou S, Lu C, Bai H, Mu H*, Duan J*. Removal and adsorption mechanism of tetracycline and cefotaxime contaminants in water by NiFe2O4-COF-chitosan-terephthalaldehyde nanocomposites film. Chemical Engineering Journal 2020, 382:123008.
8. Qiu Y, Lu C, Chen P, Sun F, Wang D, Wang Z, Hou C, Mu H*, Duan J*. Synergistic clearance of intracellular pathogens by hyaluronan-streptomycin micelles encapsulated with rapamycin. Carbohydrate Polymers 2019, 210:364-371.
9. Wang Z, Qiu Y, Hou C, Wang D, Sun F, Li X, Wang F, Yi H, Mu H*, Duan J*. Synthesis of hyaluronan-amikacin conjugate and its bactericidal activity against intracellular bacteria in vitro and in vivo. Carbohydrate Polymers 2018, 181:132-140.
10. Hou C, Bai H, Wang Z, Qiu Y, Kong LL, Sun F, Wang D, Yin H, Zhang X, Mu H*, Duan J*. A hyaluronan-based nanosystem enables combined anti-inflammation of mTOR gene silencing and pharmacotherapy. Carbohydrate Polymers 2018, 195:339-348.
六、联系方式
通讯地址:西北农林科技大学化学与药学院理科楼C202
邮箱:mhb1025@nwafu.edu.cn