一、个人简介
涂琴，女，汉族，生于1987年3月，湖北荆州人，中共党员，四级教授，博士生导师。长期致力于构建功能材料促进糖尿病创面愈合的研究，目前以第一和通讯作者在J. Am. Chem. Soc., Adv. Sci., Biomaterials, Compos. Part B-Eng., Chem. Eng. J. 等国际重要期刊上发表SCI论文45篇，2023年荣获“陕西省化学优秀青年奖”，2022年入选“中国科协科技智库青年人才计划”和“陕西省高校科协青年人才托举计划”。
二、学习与工作经历
1.学习经历
2004/09-2018/06，西北农林科技大学，理学院，学士
2008/09-2013/06，西北农林科技大学，理学院，博士
2.工作经历
2013/07-2015/12，西北农林科技大学理学院，讲师
2017/12-2018/12，美国马萨诸塞大学，访问学者
2016/01-2023/12，西北农林科技大学化学与药学院，副教授
2024/01-至 今，西北农林科技大学化学与药学院，教授
三、研究课题
1. pH调控的循环肿瘤细胞捕获、释放及在线高通量分析微流控芯片，国家自然科学基金，20.0万，2016/01–2018/12，主持。
2. 基于SERS的食源性致病菌检测与分型微流控芯片构建与应用，陕西省自然科学基金面上项目，5.0万，2023/01–2024/12，主持。
3. 基于表面增强拉曼光谱-微流控芯片的高通量食品基质细菌快速检测，陕西省自然科学基金一般项目，3.0万，2020/01–2021/12，主持。
4. 基于微流控芯片高通量快速检测食品基质中的细菌，陕西省高校科协青年人才托举计划，2.0万，2022/01–2023/12，主持。
5. 打造“食源性致病菌即时检测、鉴定及杀灭一站式”平台，助力健康中国的对策研究，2022年度科技智库青年人才计划，5.0万，2022/07–2022/12，主持。
6. 治疗细菌性角膜炎生物凝胶的研究与开发，横向项目，80.0万，2023/11–2024/12，主持。
7. 伤口愈合生物凝胶的研究与开发，横向项目，60.0万，2023/10–2026/12，主持。
8. 干细胞外泌体用于Ⅱ型糖尿病患者创面愈合，横向项目，20.0万，2022/12–2025/12，主持。
四、研究领域
1.功能生物材料制备及应用
2.生命分析化学
五、开设课程
为本科讲授《有机化学》、《有机化学实验》，为研究生讲授《科研伦理与学术道德规范》
六、主要科研成果与学术论文(近5年)
[1] Keke Wang, Mao-sen Yuan, Pengxiu Dai, Jing Li, Anju Tao, Xinke Zhang*, Jinyi Wang*, Qin Tu*. ZnFe layered double hydroxide nanosheets loaded with Cu single-atom nanozymes with multi-enzyme-like catalytic activities as an effective treatment for bacterial keratitis. Advanced Science, 2025, 2411999.
[2] Yuanxiang Jing, Ting Huang, Bin Zhao, Li Zhao, Nannan Zhang, Kexin Zhang,Keke Wang, Jinyi Wang*, Jinlian Hua*, Qin Tu*. A ROS/glucose stimulated-responsive ADSCs-derived exosomes-release hydrogel system for diabetic wound healing. Chemical Engineering Journal, 2024, 487:150561.
[3] Bin Zhao, Yu Ren, Kexin Zhang, Yuchuan Dong, Keke Wang, Nannan Zhang, Jing Li, Maosen Yuan*, Jinyi Wang*, Qin Tu*. Hydroxypropyl methylcellulose reinforced bilayer hydrogel dressings containing L-arginine-modified polyoxometalate nanoclusters to promote healing of chronic diabetic wounds. Carbohydrate Polymers, 2024, 342:122396.
[4] Zuzhe Kang, Yue Zhou, Yatuan Ma, Wenji Wang, Yue Zhang, Shu-Wei Chen, Qin Tu,* Jinyi Wang,* and Mao-Sen Yuan*. Dual-Site Chemosensor for Visualizing •OH−GSH Redox and Tracking Ferroptosis-Inducing Pathways In Vivo. Anal. Chem. 2024, 96:11932−11941.
[5] Keke Wang, Pengxiu Dai, Nannan Zhang, Yuchuan Dong, Bin Zhao, Jinyi Wang*, Xinke Zhang*, Qin Tu*. An injectable hydrogel based on sodium alginate and gelatin treats bacterial keratitis through multimodal antibacterial strategy. International Journal of Biological Macromolecules, 2024, 275:133595.
[6] Ting Huang, Yingbing Zhang, Li Zhao, Yu Ren, Keke Wang, Nannan Zhang,Xiaoli Zhang, Jinyi Wang, Qin Tu*. Sodium hyaluronate hydrogel for wound healing and human health monitoring based on deep eutectic solvent. International Journal of Biological Macromolecules, 2024, 257:128801.
[7] Meng Zhang, Jianhong Zhang, Xin Che, Jingjing Jiang, Qin Tu*, Jinyi Wang*. Biomimetic mineralization-based In situ growth of AuNCs@ZIF-8 on paper fibers for visual detection of copper ions. Talanta, 2024, 268:125364.
[8] Yuanchang Li, Lingtong Zhou, Junlan Guo, Linwei Sang, Wanyi Li, Qin Tu*, Jinyi Wang*. Preparation of a nonwetting and conductive interface by gallium liquid metal micro-droplet coating. Colloids and Surfaces A-Physicochemical And Engineering Aspects, 2024, 685:133338.
[9] Zuzhe Kang#, Jingjing Jiang#, Qin Tu#, Shuaiting Liu, Yue Zhang, Dong-En Wang*, Jinyi Wang*, Mao-Sen Yuan*. Dual-Site chemosensor for monitoring ·OH-cysteine redox in cells and in vivo. Journal of the American Chemical Society, 2023, 145:507-515.
[8] Yu Ren, Ting Huang, Xinyao Zhao, Keke Wang, Li Zhao, Anju Tao, Jingjing Jiang, Maosen Yuan*, Jinyi Wang*, Qin Tu*. Double network hydrogel based on curdlan and flaxseed gum with photothermal antibacterial properties for accelerating infectious wound healing. International Journal of Biological Macromolecules, 2023, 242:124715.
[9] Yajuan Deng, Tianbao Li, Qin Tu*, JinyiWang*. Highly stretchable and self-adhesive ionically cross-linked double-network conductive hydrogel sensor for electronic skin. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2023, 656:130363.
[10] Lingtong Zhou, Yuanchang Li, Qin Tu*, Jinyi Wang*. A 3D printing mold method for rapid fabrication of artificial blood vessels. Colloids and Surfaces A: Physicochemical and Engineering Aspects 662 (2023) 130952.
[11] Yu Ren, Aili Ailierken, Li Zhao, Zhuangsheng Lin, Jingjing Jiang, Balun Li, Jinyi Wang*, Jinlian Hua*, Qin Tu*. hUC-MSCs lyophilized powder loaded polysaccharide ulvan driven functional hydrogel for chronic diabetic wound healing. Carbohydrate Polymers, 2022, 288:119404.
[12] Wenkun Zhang, Ting Huang, Yu Ren, Shuai Yang, Xinyao Zhao, Maosen Yuan*, Jinyi Wang*, Qin Tu*. A multifunctional chitosan composite aerogel for PPCPs adsorption. Carbohydrate Polymers, 2022, 298:120102.
[13] Zuzhe Kang, Jiao Yang, Jingjing Jiang, Li Zhao, Yanrong Zhang, Qin Tu*, Jinyi Wang*, Mao-Sen Yuan*. Pillar[5]arenes modified tetraphenylethylene as fluorescent chemosensor for paraquat detection. Sensors and Actuators: B. Chemical, 2022, 370:132436.
[14] Jiao Yang, Shu-Wei Chen, Bingwen Zhang, Qin Tu*, Jinyi Wang*, Mao-Sen Yuan*. Non-biological fluorescent chemosensors for pesticides detection. Talanta, 2022, 240: 123200.
[15] Yilei Wang, Yingbing Zhang, Zhuangsheng Lin, Ting Huang, Wen Li, Wanxin Gong, Yuhui Guo, Jianmin Su, Jinyi Wang*, Qin Tu*. A green method of preparing a natural and degradable wound dressing containing aloe vera as an active ingredient. Composites Part B-Engineering, 2021, 222:109047.
[16] Yadan Guo, Yi Luo, Minggen Tang, Meng Zhang, Mao-sen Yuan, Shuwei Chen, Qin Tu*, Jinyi Wang*. Gold nanosensor for the selective identification of Escherichia coli in foodstuff and its antibacterial ability. Sensors and Actuators: B. Chemical, 2021, 34:130191.
[17] Bo Gao, Guoqiang Li, Lingtong Zhou, Yan Guo, Qin Tu*, Jinyi Wang*. On-chip screening of chemically induced mutant strains and assay of their metabolites by liquid chromatography tandem mass spectrometry. Sensors and Actuators: B. Chemical, 2021, 348:130655.
[18] Wen Li, Xinyao Zhao, Ting Huang, Yu Ren, Wanxin Gong, Yuhui Guo, Jinyi Wang*, Qin Tu*. Preparation of sodium hyaluronate/dopamine/AgNPs hydrogel based on the natural eutetic solvent as an antibaterial wound dressing. International Journal of Biological Macromolecules, 2021,191, 60-70.
[19] Wenkun Zhang, Ting Huang, Yu Ren, Yilei Wang, Ruijin Yu, Jinyi Wang*, Qin Tu*. Preparation of chitosan crosslinked with metal-organic framework (MOF-199)@aminated graphene oxide aerogel for the adsorption of formaldehyde gas and methyl orange. International Journal of Biological Macromolecules, 2021, 193: 2243-2251.
[20] Qingmiao Zhang, Zhuangsheng Lin, Wenkun Zhang, Ting Huang, Jingjing Jiang, Yu Ren, Ruiqi Zhang, Wen Li, Xiaoli Zhang*, Qin Tu*. Fabrication of green poly(vinyl alcohol) nanofibers using natural deep eutectic solvent for fast-dissolving drug delivery. RSC Advance, 2021, 11, 1012.
[21] Yilei Wang, Yingbing Zhang, Jianmin Su, Xiaoli Zhang, Jinyi Wang*, Qin Tu*. Preparation of multifunctional wound dressing based on a natural deep eutectic solvent. Acs Sustainable Chemistry & Engineering, 2020, 37:14243-14252.
[22] Qin Tu, Zhuangsheng Lin, Jinning Liu, Haochen Dai, Tianxi Yang, Jinyi Wang, Eric Decker, David Julian McClements, Lili He*. Multi-phase detection of antioxidants using surface-enhanced Raman spectroscopy with a gold nanoparticle-coated fiber. Talanta, 2020, 206:120197.
七、联系方式
通讯地址：西北农林科技大学（北校区）化学与药学院（C308）
邮编：712100
电话：18702996824
邮箱：tuqin@nwsuaf.edu.cn
