一、个人简介
常明欣，男，三级教授，博士生导师，中国化学会高级会员。主要从事手性胺类化合物的不对称催化合成和手性膦配体的设计工作，先后主持陕西省杰出青年基金、国家自然科学基金等项目的研究工作，以通讯作者在Angewandte Chemie International Edition、Nature Communications等中科院一区杂志发表研究论文十余篇，授权国家发明专利4项。
二、学习与工作经历
本科和博士分别毕业于中国科学技术大学、美国新泽西州立大学。
三、研究课题
1.“不对称催化合成”，陕西省杰出青年基金；
2.“不对称还原胺化”，国家自然科学基金；
3. “不对称还原胺化合成LW1005-296研究”，横向项目。
四、研究领域
1. 手性胺类化合物的不对称催化合成
2. 手性膦配体的设计
3. 不对称氢化合成手性药物
五、开设课程
为本科讲授《有机立体化学》，为研究生讲授《不对称合成》、《药学前沿》。
六、代表性科研成果
1. Wang, Jing; Wang, Wenji; Huang, Haizhou; Ma, Zhiqing; Chang, Mingxin.* Direct synthesis of chiral b-arylamines via additive free asymmetric reductive amination enabled by tunable bulky phosphoramidite ligands. Chemical Science, 2024, 15, 15811–15818.
2. Zhao, Wei; Wang, Wenji; Zhou, Huan; Liu, Qishan; Ma, Zhiqing; Huang, Haizhou; Chang, Mingxin.* “An Asymmetric Hydrogenation/ N-Alkylation Sequence for a Step-Economical Route to Indolizidines and Quinolizidines”. Angewandte Chemie International Edition, 2023, 62, e202308836.
3. Wu, Zitong; Wang, Wenji; Guo, Haodong; Gao, Guorui; Huang, Haizhou; Chang, Mingxin.* “Iridium-catalyzed direct asymmetric reductive amination utilizing primary alkyl amines as the N-sources”, Nature Communications, 2022, 13, 3344.
4. Gao, Zhaofeng; Liu, Jingwen; Huang, Haizhou; Geng, Huiling;* Chang, Mingxin.* “An Iridium Catalytic System Compatible with Inorganic and Organic Nitrogen Sources for Dual Asymmetric Reductive Amination Reactions”, Angewandte Chemie International Edition, 2021, 60, 27307−27311.
5. Yuan, Shuai; Gao, Guorui; Wang, Lili; Liu, Cungang; Wan, Lei; Huang, Haizhou;* Geng, Huiling;* Chang, Mingxin.* “The combination of asymmetric hydrogenation of olefins and direct reductive amination”, Nature Communications, 2020, 11, 621.
6. Wu, Zitong; Du, Shaozhi; Gao, Guorui; Yang, Wenkun; Huang, Haizhou; Chang, Mingxin.* “Secondary amines as coupling partners in direct catalytic asymmetric reductive amination”, Chemical Science, 2019, 10, 4509−4514.
7. Zhou, Huan; Liu, Yuan; Yang, Suhua; Zhou, Le; Chang, Mingxin.* “One-pot N-Boc Deprotection and Catalytic Intramolecular Asymmetric Reductive Amination for the Synthesis of Tetrahydroisoquinolines”, Angewandte Chemie International Edition, 2017, 56, 2725−2729.
8. Huang, Haizhou; Liu, Xiaoyan; Zhou, Le;* Chang, Mingxin;* Zhang, X. “Direct Asymmetric Reductive Amination for the Synthesis of Chiral b-Arylamines”, Angewandte Chemie International Edition, 2016, 55, 5309−5312. (Highlighted by Synfacts, 2016, 12, 0609, Organic Chemistry, X-MOL and Advanced Science News)
9. Chang, M.; Huang, Y.; Liu, S.; Chen, Y.;* Krska, S. W.; Davies, I. W.; Zhang, X.* “Asymmetric Hydrogenation of Pyridinium Salts with an Iridium Phosphole Catalyst”, Angewandte Chemie International Edition, 2014, 53, 12761. (Highlighted by Synfacts, 2014, 10, 1291)
10. Chang, M.; Li, W.; Zhang, X.* “A Highly Efficient and Enantioselective Access to Tetrahydroisoquinoline Alkaloids via Asymmetric Hydrogenation with an Iridium Catalyst”, Angewandte Chemie International Edition, 2011, 50, 10679.
七、联系方式
通讯地址：西北农林科技大学（北校区）化学与药学院C406
邮编：712100
邮箱：mxchang@nwsuaf.edu.cn
