一、个人简介
谢卫青，男，汉族，生于1979年3月，江西樟树人，三级教授，博士生导师。国家优秀青年科学基金获得者，荣获“Thieme Chemistry Journals Award”国际学术奖。先后主持获批国家自然科学基金项目7项，参与科技部国家重点研发计划课题1项，在J. Am. Chem. Soc.、Angew. Chem., Int. Ed.、ACS Catalysis.、Org. Lett.等国际学术期刊发表论文60余篇，出版《有机合成研究进展》教材1部，授权国家发明专利2项。
二、学习与工作经历
1.学习经历
1998.09-2002.07 兰州大学，有机化学专业，学士学位，导师：陈保华教授；
2002.09-2007.07 中科院上海有机化学研究所，有机化学专业，博士学位，导师：马大为院士。
2.工作经历
2007.08-2009.08 中科院上海有机化学研究所，生命有机国家重点实验室工作，助理研究员；
2009.09-2011.08 美国达拉斯西南医学中心，从事博士后研究；
2011.09-2015.06 中科院上海有机化学研究所，生命有机国家重点实验室工作，副研究员；
2015.07-至今 西北农林科技大学，化学与药学院，教授。
三、研究课题
1. 国家自然科学基金面上基金（项目编号：22571256，2026年-2029年，50万元）；
2. 国家自然科学基金面上基金（项目编号：22371231，2024年-2027年，50万元）；
3. 国家自然科学基金面上基金（项目编号：22171229，2022年-2025年，60万元）；
4. 国家自然科学基金优秀青年基金（项目编号：21722206， 21722206，2018年-2020年，130万元）；
5. 国家自然科学基金面上基金（项目编号：21672171，2017年-2020年，65万元）；
6. 西北农林科技大学卓越人才计划（2016年-2019年，70万元）；
7. 西北农林科技大学人才启动经费（2015年-2019年，80万元）；
8. 国家自然科学基金面上基金（项目编号：21372239，2014年-2017年，80万元）；
9. 国家自然科学基金青年基金（项目编号：21202187，2013年-2015年，25万元）。
四、研究领域
1. 不对称反应研究及其在天然产物全合成中的应用；
2. 具有重要生理活性的复杂天然产物合成；
3. 基于天然产物的化学生物学研究。
五、开设课程
《有机合成研究进展》、《有机合成实验》
六、主要科研成果与学术论文
1. Dual Photoredox/CpTi(IV)-Catalyzed Reductive Cyclization of Tertiary Bromide with Nitrile for Constructing 4a,9a-Heterocycle-Fused Tetrahydrocarbazole, Yanxia Zhen, Zhijiang Ma, Guanghui Fan, Xiaoran Shi, Junhan Chen, Jiyou Huo*, Jiahang Yan*, Weiqing Xie*, Org. Lett. 2026, 28, 2236-2241.
2. Synthetic study of arcutine diterpenoid alkaloids: rapid construction of tetracyclo[5.3.3.04,9.04,12]tridecane framework via intramolecular Diels–Alder/retro-Diels–Alder/Diels–Alder cascade, Wei Jiang, Guanghui Fan, Zhijiang Ma, Zhaozhi Zhu, Gege Zhao, Pengpeng Gao, Peiwen Yang, Jiangang Gan*, Hongbo Wei*, Weiqing Xie*, Tetrahedron Lett. 2026, 155952.
3. Efficient Construction of the Core Pentacyclic Skeleton of Communesin Alkaloids. Zhitong Yang, Hengqian Song, Pan Lei, Jiahang Yan*, Weiqing Xie*, Chin. J. Org. Chem. 2025, 45, 1003-1008.
4. Cp*Ir(III)-Catalyzed Asymmetric Tandem Intramolecular Aziridination/Aza-Semipinacol Rearrangement of Alkenyl 1,4,2-Dioxazol-5-one. Mengbo Wu,‡ Yuanzhen Xu,‡ Songlin Bai,‡ Qiqi An, Jiacheng Song, Pengpeng Gao, Jian Li, Jiyou Huo, Xiangbing Qi*, Jiahang Yan*, Weiqing Xie*, ACS Catal. 2025, 15, 10310-10319.
5. Asymmetric Synthesis of 10-Demethoxyvincorine Enabled by Dual Ni/Ti-Catalyzed Reductive Cyclization. Yanxia Zhen, ‡Wei Jiang, ‡Yuanzhen Xu, ‡Xiangyu Hui, Xiaoran Shi, Huanhuan Zou, Qianhu Chen, Junhan Chen, Hongbo Wei*, Weiqing Xie*, Org. Lett. 2025, 27, 4305-4309.
6. Construction of contiguous quaternary carbon centers enabled by dearomatization of phenols with 3-bromooxindoles. Hui Li,‡ Xi Wang,‡ Minhang Chang, Mengbo Wu, Xinyu Yuan, Xiangyu Hui, Hongbo Wei, * Juyun Xi* and Weiqing Xie* , Org. Biomol. Chem., 2024, 22, 8413-8417.
7. Synthetic Modification and Insecticidal Activity of 4-epi-cis-Dihydroagarofuran Derivatives. Ziyu Wang, Wei Jiang, Rong Tang, Hongxiang Liu, Hao Qian, Tao Guo, Jianjun Zhu, Wenjun Wu, Weiqing Xie*, Jiwen Zhang*, J. Agric. Food Chem. 2024, 72, 15552–15560.
8. A novel approach to the tetracyclic frameworks of anislactone-type sesquiterpenoids. Long He,‡ Xiaocheng Zhang,‡ Sen Li, Xuexue Tian, Yimeng Han, Haitao Xie* and Weiqing Xie*, Org. Chem. Front., 2024, 11, 4556-4559.
9. A de novo synthesis of the bisindole alkaloid geissolosimine: collective synthesis of geissoschizoline, akuammicine, (16S)-deshydroxymethylstemmadenine and Aspidospermatan alkaloids. Jiahang Yan,‡Yanxia Zhen,‡ Pengyan Wang,‡ Yimeng Han, Huanhuan Zou, Junhan Chen, Weigang He* and Weiqing Xie*, Org. Chem. Front., 2024, 11, 4556–4559.
10. Gram-scale synthesis of alstoscholarinoid B via a bio-inspired strategy. Long He,‡ Wenting Zhang,‡ Xiaocheng Zhang,‡ Xiaohui Wu, Yimeng Han, Jiahang Yan* and Weiqing Xie*, Org. Biomol. Chem. 2023, 21, 9346-9355
11. Asymmetric Synthesis of (+)-Vellosimine Enabled by a Sequential Nucleophilic Addition/Cyclization Process. Huanhuan Zou, Jiahang Yan*, Xiaocheng Zhang, Xiaohui Wu, Jiyou Huo, Yuanzhen Xu*, and Weiqing Xie*, Org. Lett., 2023, 25, 8215–8219.
12. Stereodivergent Construction of Contiguous Quaternary Carbon Centers Enabled by Asymmetric Catalysis. Jiyou Huo, Xiuhuan Li, Qianhu Chen, Pengpeng Gao, Yi Hou, Pan Lei, Huanhuan Zou, Jiahang Yan*, Xiaolong Wan*, and Weiqing Xie*, ACS Catalysis., 2023, 13, 15007-15012.
13. Catalytic Asymmetric Reverse Prenylation of Indol-2-one Enabled a Synthesis of (−)-Debromoflustramine A. Yi Hou, Jiyou Huo, Ruoxin Li, Jun Hou, Pan Lei, Hongbo Wei*, and Weiqing Xie*, Org. Lett. 2023, 25, 6949–6953.
14. A formal synthesis of (–)-erinacine B enabled by asymmetric organocatalysis. Jiahang Yan,‡ Dongyang Xu,‡ Zhiqiang Zhou,‡ Long He, Jin-Ming Gao,* Hongbo Wei* and Weiqing Xie*, Chem. Commun., 2023, 59, 7092-7095.
15. Catalytic Asymmetric Friedel–Crafts Alkylation of Indole via In Situ Generated Indol-2-one. Yuanai Fei, Jun Hou, Huiying Song, Mei-li Yang, Pan Lei, Xiayu Ge, Hongbo Wei*, Yuanzhen Xu*, Weiqing Xie*, Eur. J. Org. Chem. 2023, 26, e202300122.
16. Catalytic asymmetric construction of C2-symmetric contiguous quaternary carbon centers enabled a concise synthesis of (−)-chimonanthidine and (−)-folicanthine. Yuanzhen Xu, Pan Lei, Yuannai Fei, Yi Hou, Guzhou Chen, Zhiqiang Zhou, Huanhuan Zou, Hongbo Wei* and Weiqing Xie*, Tetrahedron Lett., 2023, 114, 154261.
17. Convergent Synthesis of Enantioenriched ortho-Fused Tricyclic Diketones via Catalytic Asymmetric Intramolecular Vinylogous Aldol Condensation. Zhiqiang Zhou, Dongyang Xu, Wei Jiang, Junhan Chen, Yanxia Zhen, Jiyou Huo, Jiahang Yan*, Jinming Gao* and Weiqing Xie*, Org. Lett. 2022, 24, 49, 9017-9022.
18. Enantioselective direct vinylogous Michael addition for constructing enantioenriched γ,γ-dialkyl substituted butyrolactams and octahydroindoles. Jiahang Yan, Wenting Zhang, Qiaoqiao He, Jun Hou, Hongxin Zeng, Hongbo Wei* and Weiqing Xie*, Org. Biomol. Chem., 2022, 20, 2387-2391.
19. A concise synthesis of herbertenolide. Jiadong Hu, Kai Ji, Lihong Yan, Siyu Yang, Yin Li, Wen Wen, Le Chen, Xiaohui Wu, Youcai Hu and Weiqing Xie*, Org. Biomol. Chem., 2022, 20, 2205-2208.
20. The applications of catalytic asymmetric halocyclization in natural product synthesis. Jiahang Yan, Zhiqiang Zhou, Qiaoqiao He, Guzhou Chen, Hongbo Wei * and Weiqing Xie*, Org. Chem. Front., 2022, 9, 499-516.
21. 2,2,2-Trifluroenthanol promoted synthesis of unsymmetrical ureas from dioxazolones and amines via tandem lossen rearrangement/condensation process, Jian Li, Wang He, Pan Lei, Jiacheng Song, Jiyou Huo, Hongbo Wei* Hongjin Bai* and Weiqing Xie*, Synth. Commun., 2021, 51(23): 3590-3600.
22. A Concise Synthesis of (-)-Dihydrospirotryprostatin B via Tandem Michael Addition. Hengqian Song, Jiacheng Song, Lihong Yan, Weigang He, Pengyan Wang, Yuanzhen Xu, Hongbo Wei,* Weiqing Xie*, Tetrahedron Lett. 2021, 85, 153486-153489.
23. An Asymmetric Synthesis of (+)-Isostrychnine Based on CatalyticAsymmetric Tandem Double Michael Addition. Pengyan Wang, Junhan Chen, Weigang He, Jiacheng Song, Hengqian Song, Hongbo Wei*, and Weiqing Xie* Org. Lett. 2021, 23, 5476–5479
24. The catalytic asymmetric dearomatization of tryptamine for accessing meso-contiguous quaternary carbon centers of oligomeric cyclotryptamine alkaloids: a formal synthesis of hodgkinsine B. Hongbo Wei, Guzhou Chen, Huanhuan Zou, Zhiqiang Zhou, Pan Lei, Jiahang Yan and Weiqing Xie*. Org. Chem. Front., 2021, 8, 3255-3259.
25. Au(I)-Catalyzed Domino Cyclization of 1,6-Diynes Incorporated with Indole. Guzhou Chen, Peng-Yu Liu, Huanhuan Zou, Jiadong Hu, Xiaowu Fang, Dongyang Xu, Yu-Peng He*, Hongbo Wei*, and Weiqing Xie*. Org. Lett. 2021, 23, 2279–2284.
26. Asymmetric Synthesis of ent-Fissistigmatin C. Dongyang Xu, Jiadong Hu, Le Chen, Lu Chen, Jiang Su, Jinjin Yang, Siyu Deng, Hongli Zhang* and Weiqing Xie*. Org. Lett. 2021, 23, 93–96.
27. Asymmetricsynthesis of 9-alkyl tetrahydroxanthenones via tandem asymmetric Michael/cyclization promoted by chiral phosphoric acid. Yu-Qi Gao, Yi Hou, Junhan Chen, Yanxia Zhen, Dongyang Xu, Hongli Zhang, Hongbo Wei and Weiqing Xie*. Org. Biomol. Chem., 2021, 19, 348–354.
28. Highly enantioselective addition of aliphatic aldehydes to 2-hydroxychalcone enabled by cooperative organocatalysts, Jiadong Hu+, Yu Qi Gao+, Dongyang Xu, Le Chen, Wen Wen, Yi Hou, Lu Chen and Weiqing Xie*. Chem. Commun., 2020, 56, 10018-10021.
29. Advances in the Synthesis of Anislactone-type Sesquiterpenes. Jian Li, Long He, Zhiqiang Zhou, Yanxia Zhen, Weiqing Xie.Chin. J. Org. Chem., 2020, 40, 3166-3176.
30. Visible-light driven synthesis of polycyclic benzo[d][1,3]oxazocine from 2-aminochalcone. Yu-Qi Gao, Yi Hou, Liming Zhu, Junhan Chen, Ruoxin Li, Sheng-Yong Zhang,* Yu-Peng He* and Weiqing Xie*. Chem. Commun., 2020, 56, 6739-6742.
31. Recent progress in the total synthesis of Strychnos alkaloids. Weigang He, Pengyan Wang, Junhan Chen, Weiqing Xie*. Org. Biomol. Chem., 2020, 18, 1046–1056.
32. A bio-inspired synthesis of hybrid flavonoids from 2-hydroxychalcone driven by visible light. Yu-Qi Gao, Yi Hou, Liming Zhu, Guzhou Chen, Dongyang Xu, Sheng-Yong Zhang, Yupeng He, Weiqing Xie*. RSC Advances, 2019, 9, 29005-29009.
33. Concise syntheses of (+)-austrodoral and (+)-austrodoric acid Based on H2O2 mediated oxidative ring contraction. Hongbo Wei, Hongli Zhang, Shoule Han, Shan Mu, Ke Huang, Guzhou Chen, Weiqing Xie*. Tetrahedron Letters, 2019, 60, 150973.
34. Carboxylate phosphabetaine as a bifunctional organocatalyst for the intramolecular ring opening of oxetane. Dongyang Xu,‡ Hongbo Wei,‡ Yanxia Zhen, Yu-Qi Gao, Ruoxin Li, Xingzhou Li, Yupeng He, Zhong Zhang and Weiqing Xie*. Org. Chem. Front., 2019, 6, 1681-1685.
35. Highly Enantioselective Tandem Michael Addition of Tryptamine-Derived Oxindoles to Alkynones: Concise Synthesis of Strychnos Alkaloids. Weigang He,† Jiadong Hu,† Pengyan Wang,† Le Chen, Kai Ji, Siyu Yang, Yin Li, Zhilong Xie and Weiqing Xie*. Angew. Chem. Int. Ed., 2018, 57, 3806-3809.
36. New Strategy for Forging Contiguous Quaternary Carbon Centers via H2O2-Mediated Ring Contraction. Jiadong Hu, Xin Yu, Weiqing Xie*. Synlett 2017; 28, 2517-2524.
37. Facile Access to 2,2-Disubstituted Indolin-3-ones via Cascade Fischer Indolization/Claisen Rearrangement Reaction. Zilei Xia, Jiadong Hu, Yu-Qi Gao, Qizheng Yao* and Weiqing Xie*. Chem. Commun. 2017, 53, 7485-7488.
38. A Re2O7 catalyzed cycloetherification of monoallylic diols. Xiaolong Wan+, Jiadong Hu+, Dongyang Xu, Yang Shang, Yanxia Zhen, Chenchen Hu, Fan Xiao, Yu-Peng He*, Yisheng Lai*, Weiqing Xie*. Tetrahedron Lett., 2017, 58, 1090-1093.
39. Stereospecific Construction of Contiguous Quaternary All-Carbon Centers by Oxidative Ring Contraction. Xin Yu+, Jiadong Hu+, Zhigao Shen, Hui Zhang, Jin-Ming Gao, and Weiqing Xie*. Angew. Chem. Int. Ed., 2017, 56, 350-353.
40. Tandem allylic alcohol isomerization/oxo-Michael addition reaction promoted by Re2O7. Jiadong Hu, Dongyang Xu, Qiang Zhang, Yang Shang, Mumin Shi, Yucui Huangfu, Leilei Liu, Rong liang, Yisheng Lai,* Yupeng He,* Jin-ming Gao and Weiqing Xie*. RSC Advances 2016, 6, 52583-52586.
41. Enantioselective Bromo-oxycyclization of Silanol, Zilei Xia, Jiadong Hu, Zhigao Shen, Xiaolong Wan, Qizheng Yao, Yisheng Lai, Jin-Ming Gao, Weiqing Xie*, Org. Lett., 2016, 18, 80–83.
42. Chiral Ion-Pair Organocatalyst Promotes Highly Enantioselective 3-exo Iodo-cycloetherification of Allyl Alcohols, Zhigao Shen, Xixian Pan, Yisheng Lai, Jiadong Hu, Xiaolong Wan, Xiaoge Li, Hui Zhang, Weiqing Xie*, Chem. Sci., 2015, 6, 6986-6990.
43. Total Synthesis of (-)-Conolutinine. Xiangyang Feng, Guangde Jiang, Zilei Xia, Jiadong Hu, Xiaolong Wan, Jin-Ming Gao, Yisheng Lai*, Weiqing Xie*, Org. Lett., 2015, 17, 4428–4431.
44. Synthesis of Naked Amino-Pyrroloindoline via Direct Aminocyclization of Tryptamine,Zhigao Shen, Zilei Xia, Huijun Zhao, Jiadong Hu, Xiaolong Wan, Yisheng Lai,* Chen Zhu*, Weiqing Xie*, Org. Biomol. Chem., 2015, 13, 5381-5384.
45. Re2O7 catalyzed dienone-phenol rearrangement, Zilei Xia+, Jiadong Hu+, Zhigao Shen, Qizheng Yao*, Weiqing Xie*, RSC Adv., 2015, 5, 38499-38502.
46. Oxidative Rearrangement of Malondialdehyde: Substrate Scope and Mechanistic Insights, Xin Yu, Zheng Liu, Zilei Xia, Zhigao Shen, Xixian Pan, Hui Zhang* and Weiqing Xie*, RSC Adv., 2014, 4, 53397-53401.
47. Decarboxylative Hydroamination of Propiolic Acids with N-Heterocycles under Transition-Metal-Free Condition, Xixian Pan, Hui Zhang,* Xin Yu, Xiaolong Wan, Weiqing Xie*, Synlett. 2014, 46, 2057-2064.
48. Highly Asymmetric Bromocyclization of Tryptophol: Unexpected Accelerating Effect of DABCO-derived Bromine Complex, Huan Liu, Guangde Jiang, Xixian Pan, Xiaolong Wan, Yisheng Lai,*, Dawei Ma* and Weiqing Xie*, Org. Lett. 2014, 16, 1908-1911.
49. Highly Enantioselective Bromocyclization of Tryptamines and Its Application in the Synthesis of (-)-Chimonanthine, Weiqing Xie*, Guangde Jiang, Huan Liu, Jiadong Hu, Xixian Pan, Hui Zhang, Xiaolong Wan, Yisheng Lai*, Dawei Ma*, Angew. Chem. Int. Ed. 2013, 52, 12924-12927.
50. Diastereoselective Construction of Continuous All-Carbon Quaternary Centers via Intramolecular Oxidative Coupling Reaction, Weiqing Xie*, Hexiang Wang, Feng Fan, Junshan Tian, Zhiwei Zuo, Weiwei Zi, Kun Gao*, Dawei Ma*, Tetrhedron Lett. 2013, 54, 4392-4396.
51. Intramolecular Oxidative Coupling: Applications in Synthesis of Complex Indole Akaloid Scaffolds, Zhiwei Zuo, Weiwei Zi, Weiqing Xie*, Dawei Ma*, Chin. J. Org. Chem. 2013, 33, 869-876.
52. Asymmetric, Regioselective Bromohydroxylation of 2-Aryl-2-propen-1-ols Catalyzed by Quinine-Derived Catalysts, Ye Zhang, Hui Xing, Weiqing Xie*, Xiaolong Wan, Yisheng Lai*, Dawei Ma*, Adv. Synth. Catal. 2013, 355, 68-72.
53. Cascade annulation of malonic diamides: a concise synthesis of polycyclic pyrroloindolines, Feng Fan, Weiqing Xie*, Dawei Ma*, Chem. Commun., 2012, 48, 7571-7573.
54. Total Synthesis of Akuammiline Alkaloid (−)-Vincorine via Intramolecular Oxidative Coupling, Weiwei Zi, Weiqing Xie, Dawei Ma*, J. Am. Chem. Soc., 2012, 132, 9126-9129.
55. Construction of Polycyclic Spiroindolines via an Intramolecular Oxidative Coupling/Cyclization Cascade Reaction Process, Feng Fan, Weiqing Xie*, Dawei Ma*, Org. Lett. 2012, 14, 1405-1407.
七、联系方式
通讯地址：西北农林科技大学（北校区）化学与药学院（C306）
邮编：712100
邮箱：xiewq@nwafu.edu.cn
课题组主页：https://www.x-mol.com/groups/xieweiqing